UniprotKB/SwissProt ID: EHD2_MOUSE (Q8BH64)
Gene Name: Ehd2
Organism: Mus musculus (Mouse).
Function: Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane. Binds ATP; does not bind GTP.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein (By similarity). Note=Colocalizes with GLUT4 in intracellular tubulovesicular structures that are associated with cortical F- actin. Colocalizes
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PDB :
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