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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Gamma-enolase

UniprotKB/SwissProt ID: ENOG_RAT (P07323)

Gene Name: Eno2

Synonyms: Eno-2

Organism: Rattus norvegicus (Rat).

Function: Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity). Cell membrane (By similarity). Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00010Glycolysis / Gluconeogenesis
map04066HIF-1 signaling pathway
map03018RNA degradation
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000941

The S-nitrosylation sites of ENOG_RAT

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1270DFKSPADPSR C ITGDQLGALY ECCCCCCCCC E ECHHHHHHHH 3.71%RC0422178444-
2270DFKSPADPSR C ITGDQLGALY ECCCCCCCCC E ECHHHHHHHH 3.71%RC0419101475-
3357IGSVTEAIQA C KLAQENGWGV CCCHHHHHHH H HHHHHCCCEE 1.81%RC0422178444-
4357IGSVTEAIQA C KLAQENGWGV CCCHHHHHHH H HHHHHCCCEE 1.81%RC0419101475-