logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: ER lumen protein retaining receptor 2

UniprotKB/SwissProt ID: ERD22_HUMAN (P33947)

Gene Name: KDELR2

Synonyms: ERD2.2

Organism: Homo sapiens (Human).

Function: Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein.

Protein disease:
Disease database Database Entry Disease information
OMIM609024KDEL ENDOPLASMIC RETICULUM PROTEIN RETENTION RECEPTOR 2; KDELR2 ;;ERD2-LIKE PROTEIN 1; ELP1;
Network with metabolic pathway:
Kegg map ID Pathway Link
map05110Vibrio cholerae infection
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000133

The S-nitrosylation sites of ERD22_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
129LLLKIWKTRS C AGISGKSQLL HHHHHHHCCC C CCCCHHHHHH 3.47%HC012212679in vitro