UniprotKB/SwissProt ID: ERF3A_HUMAN (P15170)
Gene Name: GSPT1
Synonyms: ERF3A
Organism: Homo sapiens (Human).
Function: Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
| PDB : ( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. ) |