Protein Name: Endoplasmic reticulum resident protein 44
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UniprotKB/SwissProt ID: ERP44_MOUSE (Q9D1Q6)
Gene Name: Erp44
Synonyms: Kiaa0573, Txndc4
Organism: Mus musculus (Mouse).
Function: Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum lumen.
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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