Protein Name: Constitutive coactivator of PPAR-gamma-like protein 1
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UniprotKB/SwissProt ID: F120A_HUMAN (Q9NZB2)
Gene Name: FAM120A
Synonyms: C9orf10, KIAA0183, OSSA
Organism: Homo sapiens (Human).
Function: May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous- type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates to plasma membrane upon ultraviolet exposure.
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | OMIM | 612265 | FAMILY WITH SEQUENCE SIMILARITY 120, MEMBER A; FAM120A ;;CHROMOSOME 9 OPEN READING FRAME 10; |
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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