UniprotKB/SwissProt ID: FLNC_MOUSE (Q8VHX6)
Gene Name: Flnc
Synonyms: Abpl, Fln2
Organism: Mus musculus (Mouse).
Function: Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross- linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity). Cytoplasm, cytoskeleton (By similarity). Cytoplasm, myofibril, sarcomere, Z line (By similarity). Note=A small amount localizes at membranes. In striated muscle cells, it p
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