Protein Name: Glucose-6-phosphate isomerase
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UniprotKB/SwissProt ID: G6PI_HUMAN (P06744)
Gene Name: GPI
Organism: Homo sapiens (Human).
Function: Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Secreted.
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PDB :
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | HPRD | 01394 | Hemolytic anemia, chronic, and neurologic deficits, due to GPI deficiency | | HPRD | 01394 | Hemolytic anemia, chronic, due to GPI deficiency |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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