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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Glutaryl-CoA dehydrogenase, mitochondrial

UniprotKB/SwissProt ID: GCDH_MOUSE (Q60759)

Gene Name: Gcdh

Organism: Mus musculus (Mouse).

Function: Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00071Fatty acid metabolism
map00310Lysine degradation
map00380Tryptophan metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR006089
IPR006090
IPR006091
IPR006092
IPR009075
IPR009100
IPR013764
IPR013786

The S-nitrosylation sites of GCDH_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1115VLGPTIKGYG C AGVSSVAYGL CCCCCCCCCC C CCCCHHHHHH 1.93%MC1022865876in vivo
2176PRLAKGELLG C FGLTEPNHGS HHHHCCCCEE E EECCCCCCCC 2.17%MC0821278135in vitro