Protein Name: Rab GDP dissociation inhibitor alpha
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UniprotKB/SwissProt ID: GDIA_HUMAN (P31150)
Gene Name: GDI1
Synonyms: GDIL, OPHN2, RABGDIA, XAP4
Organism: Homo sapiens (Human).
Function: Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Golgi apparatus, trans-Golgi network.
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | HPRD | 02114 | Mental retardation, X-linked 41 | | HPRD | 02114 | Mental retardation, X-linked 48 |
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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