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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: GMP reductase 1

UniprotKB/SwissProt ID: GMPR1_MOUSE (Q9DCZ1)

Gene Name: Gmpr

Synonyms: Gmpr1

Organism: Mus musculus (Mouse).

Function: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Network with metabolic pathway:
Kegg map ID Pathway Link
map00230Purine metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001093
IPR005993
IPR013785
IPR015875

The S-nitrosylation sites of GMPR1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1186IKVGVGPGSV C TTRTKTGVGY EEECCCCCEE E EEEEEECCCC 3.26%MC0421278135in vitro
2316LDILGGLRST C TYVGAAKLKE HHHHHHHHHH H HHCCCCCHHH 2.45%MC0321278135in vitro