Protein Name: Phospholipid hydroperoxide glutathione peroxidase, mitochondrial
|
UniprotKB/SwissProt ID: GPX41_MOUSE (O70325)
Gene Name: Gpx4
Organism: Mus musculus (Mouse).
Function: Protects cells against membrane lipid peroxidation and cell death. Isoform mitochondrial is required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion. Cytoplasm.
| |
|
Network with metabolic pathway:
|
|
Graphical Visualization of S-nitrosylation Sites:
|
| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
|
