Protein Name: Glutathione S-transferase P
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UniprotKB/SwissProt ID: GSTP1_HUMAN (P09211)
Gene Name: GSTP1
Synonyms: FAEES3, GST3
Organism: Homo sapiens (Human).
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Mitochondrion. Nucleus. Note=The 83 N-terminal amino acids function as un uncleaved transit peptide, and arginine residues within it are crucial for mitochondrial localization.
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Protein disease:
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Disease database |
Database Entry |
Disease information | HPRD | 00614 | Glutathione S-transferase pi polymorphism, type A | HPRD | 00614 | Glutathione S-transferase pi polymorphism, type B | HPRD | 00614 | Glutathione S-transferase pi polymorphism, type C |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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