UniprotKB/SwissProt ID: H31_HUMAN (P68431)
Gene Name: HIST1H3A
Synonyms: H3FA
Organism: Homo sapiens (Human).
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Chromosome.
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