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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: High mobility group protein B1

UniprotKB/SwissProt ID: HMGB1_HUMAN (P09429)

Gene Name: HMGB1

Synonyms: HMG1

Organism: Homo sapiens (Human).

Function: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Chromosome.

PDB :
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Network with metabolic pathway:
Kegg map ID Pathway Link
map03410Base excision repair
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000135
IPR000910
IPR009071