UniprotKB/SwissProt ID: HMGB1_HUMAN (P09429)
Gene Name: HMGB1
Synonyms: HMG1
Organism: Homo sapiens (Human).
Function: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Chromosome.
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