Protein Name: High mobility group protein B1
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UniprotKB/SwissProt ID: HMGB1_MOUSE (P63158)
Gene Name: Hmgb1
Synonyms: Hmg-1, Hmg1
Organism: Mus musculus (Mouse).
Function: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm. Chromosome. Note=Associated with the plasma membrane of filipodia in process- growing cells, and also deposited into the substrate-attached material.
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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