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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: High mobility group protein B2

UniprotKB/SwissProt ID: HMGB2_MOUSE (P30681)

Gene Name: Hmgb2

Synonyms: Hmg2

Organism: Mus musculus (Mouse).

Function: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Chromosome.

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000135
IPR000910
IPR009071

The S-nitrosylation sites of HMGB2_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
123MSSYAFFVQT C REEHKKKHPD CCHHHHHHHH H HHHHHHHCCC 2.63%MC0221278135in vitro
223MSSYAFFVQT C REEHKKKHPD CCHHHHHHHH H HHHHHHHCCC 2.63%MC0222865876in vivo
3106KRPPSAFFLF C SENRPKIKIE CCCCCHHHHH H HHHHHHHHHH 5.62%MC0222865876in vivo