Protein Name: Hydroxymethylglutaryl-CoA lyase, mitochondrial
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UniprotKB/SwissProt ID: HMGCL_MOUSE (P38060)
Gene Name: Hmgcl
Organism: Mus musculus (Mouse).
Function: Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta- hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix. Peroxisome. Note=Unprocessed form is peroxisomal.
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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