logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Heterogeneous nuclear ribonucleoprotein F

UniprotKB/SwissProt ID: HNRPF_MOUSE (Q9Z2X1)

Gene Name: Hnrnpf

Synonyms: Hnrpf

Organism: Mus musculus (Mouse).

Function: Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleoplasm (By similarity).

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000504
IPR012677
IPR012996

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
2DB1 NMR - A1-105Link

The S-nitrosylation sites of HNRPF_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1267TDLFGRDLSY C LSGMYDHRYG CCCCCCCCCC C CCCCCCCCCC 1.88%MC0520925432in vivo
2290EFTVQSTTGH C VHMRGLPYKA CCCCCCCCCC E EEEEECCCCC 2.08%MC0320925432in vivo