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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Heat shock protein 105 kDa

UniprotKB/SwissProt ID: HS105_MOUSE (Q61699)

Gene Name: Hsph1

Synonyms: Hsp105, Hsp110, Kiaa0201

Organism: Mus musculus (Mouse).

Function: Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Note=Strictly cytoplasmic in neurons.

Network with metabolic pathway:
Kegg map ID Pathway Link
map04141Protein processing in endoplasmic reticulum
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001023
IPR013126

The S-nitrosylation sites of HS105_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1642RNDAKNAVEE C VYEFRDKLCG HHHHHHHHHH H HHHHHHHHCC 2.21%MC0420925432in vivo