UniprotKB/SwissProt ID: HS90B_HUMAN (P08238)
Gene Name: HSP90AB1
Synonyms: HSP90B, HSPC2, HSPCB
Organism: Homo sapiens (Human).
Function: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
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