dbSNO 2.0

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Protein Name: Hexokinase-1

UniprotKB/SwissProt ID: HXK1_MOUSE (P17710)

Gene Name: Hk1

Organism: Mus musculus (Mouse).

Function:

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Isoform HK1: Mitochondrion outer membrane; Peripheral membrane protein. Isoform HK1-SC: Membrane. Note=Isoform HK1- SC is an integral membrane protein.

Graphical Visualization of S-nitrosylation Sites:

Overview of Protein S-nitrosylation Sites with Functional and Structural Information

InterPro ID	Domain
IPR001312

The S-nitrosylation sites of HXK1_MOUSE

No.	Position	S-nitrosylated Peptide	Secondary Structure of S-nitrosylated Peptide	Solvent Accessibility of nitrosylated Site	Substrate Motifs	PubMed ID	Experiment
1	214	LPVGFTFSFP C RQSKIDEAVL	CEEEEEEEEC C CCCCCCCEEE	6.11%	MC07	21278135	in vitro
2	214	LPVGFTFSFP C RQSKIDEAVL	CEEEEEEEEC C CCCCCCCEEE	6.11%	MC07	22865876	in vivo
3	662	MPLGFTFSFP C KQTSLDCGIL	CEEEEEEEEC C CCCCCCCEEE	4.87%	MC13	21278135	in vitro
4	662	MPLGFTFSFP C KQTSLDCGIL	CEEEEEEEEC C CCCCCCCEEE	4.87%	MC13	22865876	in vivo
5	669	SFPCKQTSLD C GILITWTKGF	EECCCCCCCC C EEEEEEECCC	4.41%	MC13	24895380	-
6	669	SFPCKQTSLD C GILITWTKGF	EECCCCCCCC C EEEEEEECCC	4.41%	MC13	22865876	in vivo
7	684	TWTKGFKATD C VGHDVATLLR	EEECCCCCCC C CHHHHHHHHH	3.25%	MC01	21278135	in vitro
8	869	ILQQLGLNST C DDSILVKTVC	HHHHCCCCCC H HHHHHHHHHH	5.70%	MC05	21278135	in vitro
9	879	CDDSILVKTV C GVVSKRAAQL	HHHHHHHHHH H HHHHHHHHHH	4.08%	MC02	21278135	in vitro
10	890	GVVSKRAAQL C GAGMAAVVQK	HHHHHHHHHH H HHHHHHHHHH	2.03%	MC13	21278135	in vitro
11	942	HQTVKELSPK C TVSFLLSEDG	HHHHHHHCCC C EEEEEECCCC	5.29%	MC13	24895380	-
12	942	HQTVKELSPK C TVSFLLSEDG	HHHHHHHCCC C EEEEEECCCC	5.29%	MC13	21278135	in vitro

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