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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Epoxide hydrolase 1

UniprotKB/SwissProt ID: HYEP_MOUSE (Q9D379)

Gene Name: Ephx1

Organism: Mus musculus (Mouse).

Function: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Microsome membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein (Potential).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00980Metabolism of xenobiotics by cytochrome P450
map04976Bile secretion
map05204Chemical carcinogenesis
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000073
IPR000639
IPR010497

The S-nitrosylation sites of HYEP_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1182LSDEHVFEVI C PSIPGYGFSE CCCCCCCEEE E ECCCCCCCCC 2.33%MC1322865876in vivo