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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ig alpha-1 chain C region

UniprotKB/SwissProt ID: IGHA1_HUMAN (P01876)

Gene Name: IGHA1

Organism: Homo sapiens (Human).

Function: Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

PDB :
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Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR003006
IPR003597
IPR007110
IPR013783

The S-nitrosylation sites of IGHA1_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1204EPWNHGKTFT C TAAYPESKTP CCCCCCCEEE E EECCCCCCCC 1.81%HC1225040305in vivo
2250LALNELVTLT C LARGFSPKDV CCCCCCEEEE E EEEEEECCCE 2.92%HC0625040305in vivo
3313EDWKKGDTFS C MVGHEALPLA CCCCCCCEEE E EEECCCCCCC 1.93%HC0125040305in vivo