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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Inositol monophosphatase 1

UniprotKB/SwissProt ID: IMPA1_MOUSE (O55023)

Gene Name: Impa1

Organism: Mus musculus (Mouse).

Function: Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol- phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1- phosphate, beta-glycerophosphate, and 2'-AMP as substrates (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000146
IPR000760

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
4AS5 X-ray 2.43 A A/B/C/D1-277Link

The S-nitrosylation sites of IMPA1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1183RIVLSNMEKL C SIPIHGIRSV HHHHHHHHHH H CCCCCCEEEH 5.26%MC0421278135in vitro