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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Indolethylamine N-methyltransferase

UniprotKB/SwissProt ID: INMT_MOUSE (P40936)

Gene Name: Inmt

Synonyms: Temt

Organism: Mus musculus (Mouse).

Function: Catalyzes the N-methylation of tryptamine and structurally related compounds (By similarity). Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n- propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00380Tryptophan metabolism
map00450Selenocompound metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000940

The S-nitrosylation sites of INMT_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1231VVEKAIQDAG C QVLKCNCVSL HHHHHHHHCC C HHHHHHCCCC 2.44%MC0121278135in vitro