Protein Name: Ras GTPase-activating-like protein IQGAP1
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UniprotKB/SwissProt ID: IQGA1_HUMAN (P46940)
Gene Name: IQGAP1
Synonyms: KIAA0051
Organism: Homo sapiens (Human).
Function: Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane.
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PDB :
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | OMIM | 603379 | IQ MOTIF-CONTAINING GTPase-ACTIVATING PROTEIN 1; IQGAP1 ;;RASGAP-LIKE WITH IQ MOTIFS;; p195; |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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