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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Integrin beta-2-like protein

UniprotKB/SwissProt ID: ITB2L_MOUSE (Q3UV74)

Gene Name: Itgb2l

Organism: Mus musculus (Mouse).

Function: During inflammatory stimulation, plays a role in retaining Cxcl13-expressing cells at the site of the inflammatory response.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane; Single-pass type I membrane protein. Note=In unactivated neutrophils, the majority of the protein is contained in intracellular granules and is released to the cell surface following inflammatory activation or induction of necrotic or apop

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map05134Legionellosis
map05144Malaria
map04650Natural killer cell mediated cytotoxicity
map04670Leukocyte transendothelial migration
map05133Pertussis
map05140Leishmaniasis
map05146Amoebiasis
map05150Staphylococcus aureus infection
map05323Rheumatoid arthritis
map05416Viral myocarditis
map04145Phagosome
map04514Cell adhesion molecules (CAMs)
map04810Regulation of actin cytoskeleton
map05152Tuberculosis
map05166HTLV-I infection
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001169
IPR002035
IPR002369
IPR003659
IPR012012
IPR012896
IPR013032
IPR013111
IPR015441
IPR015812

The S-nitrosylation sites of ITB2L_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1612RCLKDNSAIK C RECWNLLFSN CCCCCCCEEE C CCCCCCCCCC 3.46%MC0122865876in vivo