Protein Name: Intelectin-1
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UniprotKB/SwissProt ID: ITLN1_HUMAN (Q8WWA0)
Gene Name: ITLN1
Synonyms: INTL, ITLN, LFR
Organism: Homo sapiens (Human).
Function: Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Enriched in lipid rafts (By similarity).
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | OMIM | 609873 | INTELECTIN 1; ITLN1 ;;INTL;; LACTOFERRIN RECEPTOR; LFR;; HL1 |
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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