Protein Name: Junctophilin-1
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UniprotKB/SwissProt ID: JPH1_MOUSE (Q9ET80)
Gene Name: Jph1
Synonyms: Jp1
Organism: Mus musculus (Mouse).
Function: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Sarcoplasmic reticulum membrane; Single-pass type IV membrane protein. Note=Predominantly on the plasma membrane. The transmembrane domain i
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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