logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: cAMP-dependent protein kinase type II-beta regulatory subunit

UniprotKB/SwissProt ID: KAP3_HUMAN (P31323)

Gene Name: PRKAR2B

Organism: Homo sapiens (Human).

Function: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cell membrane. Note=Colocalizes with PJA2 in the cytoplasm and at the cell membrane.

Protein disease:
Disease database Database Entry Disease information
OMIM176912PROTEIN KINASE, cAMP-DEPENDENT, REGULATORY, TYPE II, BETA; PRKAR2B ;;PRKAR2;; RII-BETA
Network with metabolic pathway:
Kegg map ID Pathway Link
map04210Apoptosis
map04910Insulin signaling pathway
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000595
IPR002373
IPR003117
IPR012198
IPR014710