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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Creatine kinase M-type

UniprotKB/SwissProt ID: KCRM_MOUSE (P07310)

Gene Name: Ckm

Synonyms: Ckmm

Organism: Mus musculus (Mouse).

Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00330Arginine and proline metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000749
IPR014746

The S-nitrosylation sites of KCRM_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1146SIKGYTLPPH C SRGERRAVEK CCCCCCCCCC C CHHHHHHHHH 3.51%MC0221278135in vitro
2146SIKGYTLPPH C SRGERRAVEK CCCCCCCCCC C CHHHHHHHHH 3.51%MC0222865876in vivo
3254GNMKEVFRRF C VGLQKIEEIF CCHHHHHHHH H HHHHHHHHHH 1.94%MC0121278135in vitro
4283WNEHLGYVLT C PSNLGTGLRG ECCCCCEEEE C HHHHCCHHEE 2.80%MC0121278135in vitro
5283WNEHLGYVLT C PSNLGTGLRG ECCCCCEEEE C HHHHCCHHEE 2.80%MC0122865876in vivo