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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Lupus La protein

UniprotKB/SwissProt ID: LA_HUMAN (P05455)

Gene Name: SSB

Organism: Homo sapiens (Human).

Function: Binds to the 3' poly(U) terminii of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus (Probable).

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map05322Systemic lupus erythematosus
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000504
IPR002344
IPR006630
IPR011991
IPR012677
IPR014886

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
1OWX NMR - A225-334Link
1S79 NMR - A105-202Link
1S7A NMR - A1-103Link
1YTY X-ray 2.29 A A/B1-194Link
1ZH5 X-ray 1.85 A A/B1-194Link
2VOD X-ray 2.10 A A/B4-194Link
2VON X-ray 2.10 A A/B4-194Link
2VOO X-ray 1.80 A A/B4-194Link
2VOP X-ray 2.80 A A4-194Link

The S-nitrosylation sites of LA_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1232EMKSLEEKIG C LLKFSGDLDD CEEECCCCCC E EEEECCCCCC 4.60%HC0419483679in vivo