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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Galectin-9

UniprotKB/SwissProt ID: LEG9_MOUSE (O08573)

Gene Name: Lgals9

Organism: Mus musculus (Mouse).

Function: Binds galactosides. May play a role in thymocyte- epithelial interactions relevant to the biology of the thymus. Is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Secreted. Note=May also be secreted by a non-classical secretory pathway.

PDB :
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Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001079
IPR008985
IPR013320

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
2D6K X-ray 2.50 A A/B1-147Link
2D6L X-ray 2.50 A X1-147Link
2D6M X-ray 1.60 A A/B1-188Link
2D6N X-ray 2.00 A A/B1-147Link
2D6O X-ray 1.78 A X1-147Link
2D6P X-ray 2.70 A A/B1-188Link

The S-nitrosylation sites of LEG9_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
173PRFEEGGYVV C NTKQNGQWGP EEECCCCEEE E EEEECCCCCC 3.69%MC0820925432in vivo
2138HLVDTIAVSG C LKLSFITFQN HHCCEEEEEE E EEEEEEEEEC 2.06%MC0620925432in vivo
3258DATRFHINLR C GGDIAFHLNP CCCEEEEEEC C CCCEEEEEEC 8.89%MC0120925432in vivo
4325FKVAVNGQHM C EYYHRLKNLQ EEEEECCCEE E EECCCCCCHH 2.59%MC0420925432in vivo