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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Acyl-protein thioesterase 2

UniprotKB/SwissProt ID: LYPA2_MOUSE (Q9WTL7)

Gene Name: Lypla2

Organism: Mus musculus (Mouse).

Function: May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Deacylates GAP43 (By similarity). Has lysophospholipase activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (Probable).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00564Glycerophospholipid metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR003140

The S-nitrosylation sites of LYPA2_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
156TIRLPHVKYI C PHAPRIPVTL HCCCCCCEEE C CCCCEEEEEC 1.51%MC0421278135in vitro
2171GSAKDLAILQ C HGELDPMVPV CCCCCCEEEE E CCCCCCCCCH 3.90%MC0121278135in vitro
3213KTYPGVMHSS C PQEMAAVKEF EEECCCCCCC C HHHHHHHHHH 4.52%MC1321278135in vitro