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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Maleylacetoacetate isomerase

UniprotKB/SwissProt ID: MAAI_MOUSE (Q9WVL0)

Gene Name: Gstz1

Synonyms: Maai

Organism: Mus musculus (Mouse).

Function: Probable bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7- chloro-4-nitrobenz-2-oxa-1, 3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with t-butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity).

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map00350Tyrosine metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR004045
IPR004046
IPR005955
IPR010987
IPR012335
IPR012336

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
2CZ2 X-ray 1.40 A A1-216Link
2CZ3 X-ray 2.30 A A/B1-216Link

The S-nitrosylation sites of MAAI_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
116PILYSYFRSS C SWRVRIALAL CEEEEECCCC H HHHHHHHHHH 4.82%MC0421278135in vitro