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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Malate dehydrogenase, mitochondrial

UniprotKB/SwissProt ID: MDHM_MOUSE (P08249)

Gene Name: Mdh2

Synonyms: Mor1

Organism: Mus musculus (Mouse).

Function:

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00020Citrate cycle (TCA cycle)
map00620Pyruvate metabolism
map00630Glyoxylate and dicarboxylate metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001236
IPR001252
IPR001557
IPR010097
IPR015955
The S-nitrosylation sites of MDHM_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
189GYLGPEQLPD C LKGCDVVVIP EEEEECCCHH H HCCCCEEEEE 3.90%MC0622178444-
289GYLGPEQLPD C LKGCDVVVIP EEEEECCCHH H HCCCCEEEEE 3.90%MC0622588120-
389GYLGPEQLPD C LKGCDVVVIP EEEEECCCHH H HCCCCEEEEE 3.90%MC0624895380-
489GYLGPEQLPD C LKGCDVVVIP EEEEECCCHH H HCCCCEEEEE 3.90%MC0621278135in vitro
589GYLGPEQLPD C LKGCDVVVIP EEEEECCCHH H HCCCCEEEEE 3.90%MC0620837516in vivo
689GYLGPEQLPD C LKGCDVVVIP EEEEECCCHH H HCCCCEEEEE 3.90%MC0622865876in vivo
793PEQLPDCLKG C DVVVIPAGVP ECCCHHHHCC C CEEEEECCCC 3.25%MC0922588120-
893PEQLPDCLKG C DVVVIPAGVP ECCCHHHHCC C CEEEEECCCC 3.25%MC0924895380-
993PEQLPDCLKG C DVVVIPAGVP ECCCHHHHCC C CEEEEECCCC 3.25%MC0921278135in vitro
1093PEQLPDCLKG C DVVVIPAGVP ECCCHHHHCC C CEEEEECCCC 3.25%MC0922865876in vivo
11212GKTIIPLISQ C TPKVDFPQDQ CCCEEEEHEE E EECCCCCHHH 5.85%MC0822588120-
12212GKTIIPLISQ C TPKVDFPQDQ CCCEEEEHEE E EECCCCCHHH 5.85%MC0824895380-
13212GKTIIPLISQ C TPKVDFPQDQ CCCEEEEHEE E EECCCCCHHH 5.85%MC0821278135in vitro
14212GKTIIPLISQ C TPKVDFPQDQ CCCEEEEHEE E EECCCCCHHH 5.85%MC0822865876in vivo
15275AMNGKEGVVE C SFVQSKETEC HCCCCCEEEE E EEECCCCCCC 2.30%MC0222588120-
16275AMNGKEGVVE C SFVQSKETEC HCCCCCEEEE E EEECCCCCCC 2.30%MC0224895380-
17275AMNGKEGVVE C SFVQSKETEC HCCCCCEEEE E EEECCCCCCC 2.30%MC0224926564-
18275AMNGKEGVVE C SFVQSKETEC HCCCCCEEEE E EEECCCCCCC 2.30%MC0220925432in vivo
19275AMNGKEGVVE C SFVQSKETEC HCCCCCEEEE E EEECCCCCCC 2.30%MC0221278135in vitro
20275AMNGKEGVVE C SFVQSKETEC HCCCCCEEEE E EEECCCCCCC 2.30%MC0222865876in vivo
21285CSFVQSKETE C TYFSTPLLLG EEEECCCCCC C EEEEEEEEEC 4.95%MC1022588120-
22285CSFVQSKETE C TYFSTPLLLG EEEECCCCCC C EEEEEEEEEC 4.95%MC1024895380-
23285CSFVQSKETE C TYFSTPLLLG EEEECCCCCC C EEEEEEEEEC 4.95%MC1024926564-
24285CSFVQSKETE C TYFSTPLLLG EEEECCCCCC C EEEEEEEEEC 4.95%MC1020925432in vivo
25285CSFVQSKETE C TYFSTPLLLG EEEECCCCCC C EEEEEEEEEC 4.95%MC1021278135in vitro
26285CSFVQSKETE C TYFSTPLLLG EEEECCCCCC C EEEEEEEEEC 4.95%MC1022865876in vivo