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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Sodium/calcium exchanger 2

UniprotKB/SwissProt ID: NAC2_RAT (P48768)

Gene Name: Slc8a2

Synonyms: Ncx2

Organism: Rattus norvegicus (Rat).

Function: Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Multi-pass membrane protein.

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR003644
IPR004836
IPR004837

The S-nitrosylation sites of NAC2_RAT

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1537FQDRLLHVSE C MGTVDVRVVR ECCCEEEEEE C EEEEEEEEEE 2.07%RC0422178444-
2537FQDRLLHVSE C MGTVDVRVVR ECCCEEEEEE C EEEEEEEEEE 2.07%RC0416418269in vitro