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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Nascent polypeptide-associated complex subunit alpha, muscle-specific form

UniprotKB/SwissProt ID: NACAM_MOUSE (P70670)

Gene Name: Naca

Synonyms: Gm1878

Organism: Mus musculus (Mouse).

Function: Cardiac- and muscle-specific transcription factor. May act to regulate the expression of genes involved in the development of myotubes. Plays a critical role in ventricular cardiomyocyte expansion and regulates postnatal skeletal muscle growth and regeneration. Involved in the organized assembly of thick and thin filaments of myofibril sarcomeres.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus.

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002715
IPR004829
IPR015940

The S-nitrosylation sites of NACAM_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1354KGSSAVTNEL C SPPGSSNVAG CCCCHHHHCC C CCCCCCCCEE 4.71%MC1321278135in vitro
21763DSHISPVSDA C STGTTTPQAS CCCCCCCCCC C CCCCCCCCCC 4.49%MC1321278135in vitro
31820ANSNSASSPK C PDPSSKKDTK CCCCCCCCCC C CCCCCCCCCC 5.40%MC0221278135in vitro
41866LLVSPAKGSD C LHSPKGPVGS CCCCCCCCCC C CCCCCCCCCC 3.84%MC0421278135in vitro