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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1

UniprotKB/SwissProt ID: NDUA1_MOUSE (O35683)

Gene Name: Ndufa1

Organism: Mus musculus (Mouse).

Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion inner membrane; Single-pass membrane protein; Matrix side (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00190Oxidative phosphorylation
map05010Alzheimer's disease
map05012Parkinson's disease
map05016Huntington's disease
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

The S-nitrosylation sites of NDUA1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
115ILPGLAIMGV C LVIPGVSTAY HCCHHHHHHH H HHHCCCHHHE 1.76%MC1322865876in vivo