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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

UniprotKB/SwissProt ID: NDUA8_MOUSE (Q9DCJ5)

Gene Name: Ndufa8

Organism: Mus musculus (Mouse).

Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion (By similarity). Mitochondrion intermembrane space (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00190Oxidative phosphorylation
map05010Alzheimer's disease
map05012Parkinson's disease
map05016Huntington's disease
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR010625

The S-nitrosylation sites of NDUA8_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
136KAAAHHYGAQ C DKTNKEFMLC HHHHHHHCCC C CCCCHHHHCC 6.01%MC0422865876in vivo
246CDKTNKEFML C RWEEKDPRRC CCCCCHHHHC C CCCCCCHHHH 2.97%MC0322865876in vivo
366CLKEGKLVNG C ALNFFRQIKS HHHHCHHHHH H HHHHHHHHHH 3.08%MC0222588120-