Protein Name: NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
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UniprotKB/SwissProt ID: NDUS6_HUMAN (O75380)
Gene Name: NDUFS6
Organism: Homo sapiens (Human).
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
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Protein disease:
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Disease database |
Database Entry |
Disease information | KEGG | H00473 | Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency ( | OMIM | 252010 | MITOCHONDRIAL COMPLEX I DEFICIENCY ;;NADH:Q(1) OXIDOREDUCTASE DEFICIENCY;; NADH-COENZYME Q R | OMIM | 603848 | NADH-UBIQUINONE OXIDOREDUCTASE Fe-S PROTEIN 6; NDUFS6 ;;COMPLEX I, MITOCHONDRIAL RESPIRATORY | HPRD | 10356 | Mitochondrial complex I deficiency |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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