UniprotKB/SwissProt ID: NELFA_HUMAN (Q9H3P2)
Gene Name: NELFA
Synonyms: WHSC2
Organism: Homo sapiens (Human).
Function: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Probably required to interact with the RNA polymerase II complex.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.
| |
|
