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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Nuclear factor of activated T-cells 5

UniprotKB/SwissProt ID: NFAT5_HUMAN (O94916)

Gene Name: NFAT5

Synonyms: KIAA0827, TONEBP

Organism: Homo sapiens (Human).

Function: Transcription factor involved in the transcriptional regulation of osmoprotective and inflammatory genes. Regulates hypertonicity-induced cellular accumulation of osmolytes.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm (By similarity). Note=Nuclear distribution increases under hypertonic conditions (By similarity).

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map04360Axon guidance
map04370VEGF signaling pathway
map04650Natural killer cell mediated cytotoxicity
map04660T cell receptor signaling pathway
map04662B cell receptor signaling pathway
map04310Wnt signaling pathway
map05161Hepatitis B
map05166HTLV-I infection
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000451
IPR002909
IPR008366
IPR008967
IPR011539
IPR013783
IPR014756
IPR015646