logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Oxygen-insensitive NADPH nitroreductase

UniprotKB/SwissProt ID: NFSA_ECOLI (P17117)

Gene Name: nfsA

Synonyms: mda18, mdaA, ybjB

Organism: Escherichia coli (strain K12).

Function: Reduction of nitroaromatic compounds using NADH. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. Major component of the oxygen- insensitive nitroreductase activity in E.coli.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000415

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
1F5V X-ray 1.70 A A/B1-240Link

The S-nitrosylation sites of NFSA_ECOLI

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
19--MTPTIELI C GHRSIRHFTD --CCHHHHHH H HHHHHCCCCC 6.16%EC0222178444-
29--MTPTIELI C GHRSIRHFTD --CCHHHHHH H HHHHHCCCCC 6.16%EC0219483679in vitro