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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Nitrile hydratase subunit alpha

UniprotKB/SwissProt ID: NHAA_RHOER (P13448)

Gene Name: nthA

Organism: Rhodococcus erythropolis (Arthrobacter picolinophilus).

Function: NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR004232

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
1AHJ X-ray 2.65 A A/C/E/G1-207Link
2AHJ X-ray 1.70 A A/C2-207Link
2CYZ X-ray 1.55 A A2-206Link
2CZ0 X-ray 1.50 A A2-206Link
2CZ1 X-ray 1.39 A A2-206Link
2CZ6 X-ray 1.50 A A2-206Link
2CZ7 X-ray 1.80 A A2-206Link
2D0Q X-ray 1.65 A A2-206Link
2QDY X-ray 1.30 A A1-207Link
2ZCF X-ray 1.43 A A2-207Link
2ZPB X-ray 1.30 A A2-207Link
2ZPE X-ray 1.48 A A2-207Link
2ZPF X-ray 1.48 A A2-207Link
2ZPG X-ray 1.39 A A2-207Link
2ZPH X-ray 1.59 A A2-207Link
2ZPI X-ray 1.49 A A2-207Link
3A8G X-ray 1.11 A A1-207Link
3A8H X-ray 1.66 A A1-207Link
3A8L X-ray 1.63 A A1-207Link
3A8M X-ray 1.32 A A1-207Link
3A8O X-ray 1.47 A A1-207Link

The S-nitrosylation sites of NHAA_RHOER

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1113TLKNVIVCSL C SCTAWPILGL CEEEEEEEEE E CCCCCCCCCC 1.48%N/A22178444-
2113TLKNVIVCSL C SCTAWPILGL CEEEEEEEEE E CCCCCCCCCC 1.48%N/A9368004-