Protein Name: Nitrilase homolog 1
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UniprotKB/SwissProt ID: NIT1_MOUSE (Q8VDK1)
Gene Name: Nit1
Organism: Mus musculus (Mouse).
Function: Plays a role in cell growth and apoptosis: loss of expression promotes cell growth, resistance to DNA damage stress and increased incidence to NMBA-induced tumors. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T- cells. Has apparently no omega-amidase activity such as NIT2.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Mitochondrion.
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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