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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Vesicle-fusing ATPase

UniprotKB/SwissProt ID: NSF_MOUSE (P46460)

Gene Name: Nsf

Synonyms: Skd2

Organism: Mus musculus (Mouse).

Function: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack GRIA2 leads to influence GRIA2 membrane cycling (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

Network with metabolic pathway:
Kegg map ID Pathway Link
map04721Synaptic vesicle cycle
map04962Vasopressin-regulated water reabsorption
map04727GABAergic synapse
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR003338
IPR003593
IPR003959
IPR003960
IPR004201
IPR009010

The S-nitrosylation sites of NSF_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
111MAGRTMQAAR C PTDELSLSNC CCCCEEEEEE C CCCCEEEEEE 3.50%MC0122588120-
221CPTDELSLSN C AVVNEKDFQS CCCCCEEEEE E EEECCCCCCC 2.46%MC0222588120-
3250FPPEIVEQMG C KHVKGILLYG HCHHHHHHCC C CCCCCEEEEC 2.01%MC0616418269in vitro
4264KGILLYGPPG C GKTLLARQIG CCEEEECCCC C CHHHHHHHHH 6.61%MC0516418269in vitro
5264KGILLYGPPG C GKTLLARQIG CCEEEECCCC C CHHHHHHHHH 6.61%MC0519101475-
6599FDDAYKSQLS C VVVDDIERLL HHHHHHCCCC E EEEECHHHHC 3.51%MC1322588120-