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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Endonuclease G, mitochondrial

UniprotKB/SwissProt ID: NUCG_MOUSE (O08600)

Gene Name: Endog

Organism: Mus musculus (Mouse).

Function: Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion.

Network with metabolic pathway:
Kegg map ID Pathway Link
map04210Apoptosis
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001604

The S-nitrosylation sites of NUCG_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1110RLRGDGDRSA C DFREDDSVHA CCCCCCCCCC C CCCCCCCCCH 5.54%MC0321278135in vitro
2193LTRTYQNVYV C TGPLFLPRTE HHHHCCCEEE E ECCEECCCCC 1.67%MC1321278135in vitro
3193LTRTYQNVYV C TGPLFLPRTE HHHHCCCEEE E ECCEECCCCC 1.67%MC1322865876in vivo