UniprotKB/SwissProt ID: NUCL_MOUSE (P09405)
Gene Name: Ncl
Synonyms: Nuc
Organism: Mus musculus (Mouse).
Function: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus, nucleolus. Cytoplasm (By similarity). Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs (By similarity).
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